ATTR-CM is a serious, underrecognized, and
underdiagnosed type of amyloidosis that
affects the heart and is associated with heart
ATTR-CM is a serious, underrecognized, and underdiagnosed type of amyloidosis that affects the heart and is associated with heart failure.
Watch the video or scroll down to learn more.
The liver produces transthyretin, a transport protein that carries the hormone thyroxine and vitamin A (retinol) throughout the bloodstream.
When someone has ATTR-CM, either due to aging (wild-type) or an inherited genetic variant (hereditary), the protein becomes unstable and misfolds.
Over time, the misfolded proteins join together and build up in the body, including in the heart (causing the heart muscle to thicken and stiffen, eventually leading to heart failure).
hATTR-CM IS PASSED DOWN FROM A RELATIVE AND IS CAUSED BY A CHANGE (OR “MUTATION”) IN ONE OF YOUR GENES.
TELL YOUR DOCTOR IF YOU HAVE A FAMILY HISTORY OF ATTR-CM AND/OR UNRESOLVED HEART FAILURE.
ATTR-CM could be the underlying cause of your heart failure, so it’s
important to recognize the messages your heart may be sending.
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